HIV stigma and discrimination is well recognised as a global systemic barrier to effective HIV prevention, testing, treatment and care. Almost all PLHIV have a personal story of how stigma has discounted, constrained and impaired their full participation in civil society.
The ENUF campaign provides a platform for anyone to speak about their experiences of HIV stigma and resilience and have their voice heard through social marketing and media promotion. This innovative crowdsourced and crowdfunded protest campaign focuses on challenging stereotypes, assumptions and the unfairness of discrimination while promoting resilient behaviours and experiences. The campaign speaks truth to the endurance of stigma by encouraging people to submit their personal experiences. The entire community including businesses, organisations and individuals has been invited and enlisted to support and promote the campaign in order to shed light on the multiple manifestations of stigma and to share their experiences using both traditional and new media formats.
Launched at ASHM in 2012, the campaign has gathered upwards of 60 submissions from individuals, which have become the text for over 40 campaign messages. Over 2000 people have signed the ENUF pledge and the campaign is reaching over 500 individuals direct through Facebook and Twitter with a reach of 163,231 individuals. Additionally, eight high profile ambassadors have been recruited to spread the word about the campaign, to encourage participation and speak directly to the effects of HIV stigma.
The campaign continues to grow and expand its reach into the community. Feedback from individuals has shown how powerful and persuasive the voices of the lived experiences of stigma and resilience are making to affect social change.
HIV-associated leishmaniasis, endemic in the Mediterranean basin is a growing problem in India, Brazil and East Africa. Despite surviving for than 20 years, the clinical course of our visceral-leishmania (VL)-HIV co-infected patient illustrates several management challenges including diagnosis, speciation and drug resistance; monitoring burden of disease; access to and use of VL-treatments; end-organ toxicity and the combined immunosuppressive effects of HIV-VL.
Adherence to combination antiretroviral therapy (cART ) plays an important role on treatment outcomes. The TREAT Asia Studies to Evaluate Resistance – Monitoring Cohort Study (TASER-M) collects patients’ adherence based on a Visual Analogue Scale. The aim of this analysis was to assess the rates of, and factors associated with, suboptimal adherence in the first 24 months of initial cART in Asian patients.
REACH was a collaborative research and practice initiative to develop evidence building frameworks, capacity, tools and resources with the Victorian HIV community partnership.
HIV disease is associated with chronic inflammation and activation of the innate immune system. This state, as measured using plasma markers of inflammation, persists following suppression of HIV viremia using antiretroviral therapy, and may increase risk of non-AIDS co-morbidities. The causes of innate immune activation in the setting of virological suppression are unclear. Natural killer (NK) cells are innate immune cells that kill virus-infected and transformed cells without prior sensitization. We have shown that NK cells are activated both phenotypically (elevated expression of HLA-DR) and functionally (increased spontaneous degranulation measured by CD107a surface expression) in virologically suppressed (VS) HIV+ individuals. NK cells also lose expression of CD16, the receptor which mediates antibody-dependent cellular cytotoxicity.
Regular HIV testing is recommended in men who take sexual risks. We assessed the relationship between perceived barriers to HIV testing, and frequency of testing among men who engaged in unprotected anal intercourse with casual partners (UAIC), to inform HIV testing strategies.
The majority of HIV diagnoses including delayed diagnoses in Australia occur among men who report homosexual contact – hereafter called gay and bisexual men (GBM). Delayed diagnosis is strongly associated with increased HIV-related mortality and morbidity. People who are unaware of their HIV-positive status may also be unwittingly transmitting HIV. We assessed trends in delayed HIV diagnoses among GBM in Australia.
Background: People Living with HIV (PLHIV) who are transitioning from custodial settings are at risk of experiencing treatment interruptions and loss to follow up for vital HIV care. The NSW Persons In Custody HIV Community Referral Project (PICHCRP) aims to ensure PLHIV who are transitioning from custodial settings back into the community receive seamless HIV service, care and support.