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Trends in CD4+ cell count at HIV diagnosis in Australia, 2001-2012.

Trends in CD4+ cell count at HIV diagnosis in Australia, 2001-2012.

Methods: Cases of newly diagnosed HIV infection are notifiable in each state/territory in Australia and then forwarded to the National HIV Registry for national collation and analysis. Information is routinely collected on date of HIV diagnosis, CD4+ cell count and newly acquired HIV status. Cases previously diagnosed overseas were excluded from analyses.

Results: Mean CD4+ cell count was 453 cells/μl in 2001–2006 and 450 in 2007–2012. Among 3,466 (30%) cases of newly acquired infection, 60% and 56% diagnosed in 2001-2006 and 2007-2012, respectively, had a CD4+ cell count of 500 or higher, and less than 5% had a CD4+ cell count of less than 200 in 2001-2012. Among cases without evidence of newly acquired infection, mean CD4+ cell count was 396 in 2001-2006 and 398 in 2007-2012. The proportion of non-newly acquired cases with a CD4+ cell count of less than 200 declined from 32% in 2001 to 24% in 2007-2008 and increased to 27% in 2012. The proportion of non-newly acquired cases among men who have sex with men whose CD4+ cell count was less than 200 remained stable at around 20% in 2001 – 2012. Among cases attributed to injecting drug use or heterosexual contact, 24% and 30%, respectively, were diagnosed with a CD4+ cell count of less than 200.

Conclusion: The distribution of CD4+ cell count at HIV diagnosis has remained relatively stable over the last 12 years. HIV diagnosis at advanced HIV infection continues to occur in Australia at moderate levels.

Speakers: Ann McDonald
Conference: AIDS 2013, HIV
Areas of Interest / Categories: Australian Society for HIV 2015

Australian Society for HIV 2015

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