The male sex organ is the most frequent target organ for occurring Erectile Dysfunction (ED); ED pioneers other serious diseases queuing in the male holistic body system… ED indicates as “Gate-way” to other more serious Degenerative Diseases, such as; Critical limb ischemia, Hypertension, Dyslipidemia, Stroke, Cardio-Vascular-Diseases, Diabetes type-2, Kidney Failures, Hypogonadism and more…..
Hypogonadism accelerates the process of Precocious Aging; expressing Syndromes of Metabolic (METS) and Testosterone Deficiency (TDS). Endothelial Progenitor Cells (EPCs) Bone-marrow-derived EPCs has been well known for having the possibilities to regenerate sloughing off vascular- endothelium cells. EPCs have demonstrated the beneficial effects on ischemic induced vascular damage and recover ischemic tissues and organs. DHEA and Phospho-di-esterase-type-5i (PDE-5i)
Our current preliminary trials show: 1. DHEA enhance bone-marrow EPCs production in smokers and obese male hypogonadism with ED. 2. Combined daily consumption of DHEA and low dose PDE- 5i opens a new window to promote production of low levels EPCs in obese male hypogonadism and smokers with ED. Further trials with larger subjects and prolong periods of trial is recommended.