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Long term androgen therapy restores erection in Sildenafil non-responders on demand

Long term androgen therapy restores erection in Sildenafil non-responders on demand

Debate about the role of androgens in erection still exists. The aim of this study  was to assess the efficacy of long term taking  androgen in  patients who were previously sildenafil non-responder on demand regime.  In a propective controlled trial 17 patients  with ED more than 1 year non-responder on sildenafil taking  on demand were included. Average age of patients was  53.4 All patients had late onset hypogonadism (AMS score  37±6, testosterone 7,4±2,3).  All  patients were treated with Androgel 25 mg.
The efficacy of treatment measured by EF domain score on IIEF questionnaire and arterial reponse by Penile Doppler Ultrasound wich were done before treamtent and 2 months later during the treatment. Results: 11/13 patients showed not only improvement the mean score on IIEF (from 8±5 to 14±5, p<0.03) but also improvement in peak systolic  velocity up  to 16,6%±3 (p<0.04) in the end of 2nd month of treatment. In the end of 1st month only 4/13 showed improvement of erection. Conclusions:  It takes time to improve erectile function with androgen therapy.

Areas of Interest / Categories: Androgen, Androgen Therapy, WAS 2007

WAS 2007

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