Please Sign In or Create an account
Leptin, obesity and cognition

Leptin, obesity and cognition

First, we and others have shown that when presented with food-related cues, the brain processes information differently when it is on or off leptin. Then, we showed that leptin increases grey matter volume in brain areas, such as the anterior cingulate, which are relevant to addictive behaviour and to depression. We also showed in a leptin-deficient child that leptin replacement therapy drastically increased performance in subscales of neuropsychological testing. Additionally, it has been shown in the elderly that higher levels of endogenous leptin are protective against dementia. Given this exciting background supporting its pro-cognitive actions, human leptin is currently being explored as an experimental treatment for Alzheimer’s disease.

Areas of Interest / Categories: ANSA 2015

ANSA 2015

Treatment of ADHD & Autism/Asperger's using Neurotherapy

Neurofeedback Improves Visual-spatial Attention in Aspiring Elite Table Tennis Players

Previously Brown and Jamieson found that increased Mu rhythm (10-12Hz) localised at right BA6/BA13 differentiates elite from amateur table tennis players while viewing an elite opposing player. These cortical regions include nodes in both the dorsal attention network (identifying 'where' an object is in space relative to one’s body) and in the ventral attention network (identifying and selecting salient sensory information). These results suggest engagement of a timing mechanism by elite table tennis players regulating alpha oscillations relative to incoming stimuli, allowing for optimal efficiency in selecting salient information and, importantly, inhibiting irrelevant information.

Targeting the brain in chronic pain: the role of cortical body representation

Pain is frustratingly complex. Some people who have terrible injuries report very little pain while others develop terrible pain following a very minor event. This suggests that pain is not related only to the degree of physical injury and as such, other processes must contribute to the experience of pain. A growing body of evidence suggests that people in pain often have an altered perception of their body part. For example, it may feel too big or too small than its actual size. Further, people in pain have disruptions in the evaluation of incoming information from that painful body part and from the space surrounding it.

Heart rate variability (HRV) biofeedback increases vagal modulation at baseline and during orthostatic stress

HRV biofeedback produces an immediate increase in vagal modulation (cardiac risk marker) by guiding the user to adopt a slow rhythmic breathing pattern. A gap in the HRV biofeedback literature includes a lack of knowledge concerning the persistence of this increase in vagal modulation at baseline and under dynamic stress conditions. The current study aimed to assess the effect of 30 days of HRV biofeedback training on vagal modulation at baseline and during both orthostatic and mental stress.

Targeting the brain in chronic pain: the role of cortical body representation

Pain is frustratingly complex. Some people who have terrible injuries report very little pain while others develop terrible pain following a very minor event. This suggests that pain is not related only to the degree of physical injury and as such, other processes must contribute to the experience of pain. A growing body of evidence suggests that people in pain often have an altered perception of their body part. For example, it may feel too big or too small than its actual size. Further, people in pain have disruptions in the evaluation of incoming information from that painful body part and from the space surrounding it.

The Effects of QEEG Guided Neurofeedback on Post-Concussion Syndrome

This presentation describes the case of a 17 year old female athlete who suffered two consecutive concussions, producing post-concussion headache symptoms. The athlete was assessed following the initial

A systematic review of the contribution of EEG to the diagnosis of ADHD

Despite the prevalence and generally chronic course of Attention-Deficit/Hyperactivity Disorder (ADHD) throughout childhood, clinical diagnosis is dependent on traditional methods of behavioural observation with no routine biological testing to clarify the nature of the underlying neurological disorder or to inform relevant treatment. The current review briefly describes the unique neurological attributes of ADHD and the potential of neurophysiological data to inform diagnosis and assessment of ADHD and then presents a concerted effort to systematically identify all relevant primary research. After applying appropriate inclusion and exclusion criteria, 26 citations were considered eligible for this review.