ADHD insights from the Brain Resource International Database over the past decade have lead to new products that provide personalized diagnostic decision support for ADHD and allied conditions, drawing primarily on profiles of emotional functioning and cognitive performance. An overview of these insights and product tools will be provided here, as well as our ongoing extension of this program of ADHD research, which is focused on EEG & arousal biomarkers in clinical subgroups. This extension addresses the key question of mechanism and meaningful biological subgroups within ADHD and allied disorders, and the way in which these relate to treatment options and functional outcomes – with a view to identifying the most beneficial treatment approach for each individual child. In addition, an overview of a related new international study on the efficacy of Neurofeedback in ADHD, INSENTA, will also be presented.