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Leptin, obesity and cognition

Leptin, obesity and cognition

First, we and others have shown that when presented with food-related cues, the brain processes information differently when it is on or off leptin. Then, we showed that leptin increases grey matter volume in brain areas, such as the anterior cingulate, which are relevant to addictive behaviour and to depression. We also showed in a leptin-deficient child that leptin replacement therapy drastically increased performance in subscales of neuropsychological testing. Additionally, it has been shown in the elderly that higher levels of endogenous leptin are protective against dementia. Given this exciting background supporting its pro-cognitive actions, human leptin is currently being explored as an experimental treatment for Alzheimer’s disease.

Areas of Interest / Categories: ANSA, ANSA 2015

ANSA 2015

Treatment of ADHD & Autism/Asperger's using Neurotherapy

Neurofeedback Improves Visual-spatial Attention in Aspiring Elite Table Tennis Players

Previously Brown and Jamieson found that increased Mu rhythm (10-12Hz) localised at right BA6/BA13 differentiates elite from amateur table tennis players while viewing an elite opposing player. These cortical regions include nodes in both the dorsal attention network (identifying 'where' an object is in space relative to one’s body) and in the ventral attention network (identifying and selecting salient sensory information). These results suggest engagement of a timing mechanism by elite table tennis players regulating alpha oscillations relative to incoming stimuli, allowing for optimal efficiency in selecting salient information and, importantly, inhibiting irrelevant information.

Heart rate variability (HRV) biofeedback increases vagal modulation at baseline and during orthostatic stress

HRV biofeedback produces an immediate increase in vagal modulation (cardiac risk marker) by guiding the user to adopt a slow rhythmic breathing pattern. A gap in the HRV biofeedback literature includes a lack of knowledge concerning the persistence of this increase in vagal modulation at baseline and under dynamic stress conditions. The current study aimed to assess the effect of 30 days of HRV biofeedback training on vagal modulation at baseline and during both orthostatic and mental stress.

Targeting the brain in chronic pain: the role of cortical body representation

Pain is frustratingly complex. Some people who have terrible injuries report very little pain while others develop terrible pain following a very minor event. This suggests that pain is not related only to the degree of physical injury and as such, other processes must contribute to the experience of pain. A growing body of evidence suggests that people in pain often have an altered perception of their body part. For example, it may feel too big or too small than its actual size. Further, people in pain have disruptions in the evaluation of incoming information from that painful body part and from the space surrounding it.

The Effects of QEEG Guided Neurofeedback on Post-Concussion Syndrome

This presentation describes the case of a 17 year old female athlete who suffered two consecutive concussions, producing post-concussion headache symptoms. The athlete was assessed following the initial

Neurofeedback for Dyslexia

Developmental Dyslexia is the most common learning disability diagnosed in children (Ziegler et al., 2008), estimated to affect between 5 to 17.5% (Shaywitz, 1998). Longitudinal studies reveal that children with dyslexia display persistently poorer literacy than peers even after intensive intervention (e.g. Shaywitz, 2003). Neuroimaging studies reveal underactivity in the left posterior language areas of the brain in both adults and children relative to controls during phonological tasks (Hoeft et al., 2006). Advances in the use of Neurotherapy for the treatment of a range of psychological conditions (e.g. in ADHD, see Arns et al., 2009), lend support for its use as a treatment tool for normalising language function.

Heart Rate Variability Training for Dissociative Disorders