Neuroplasticity ranks as one of the most exciting findings to emerge from the “Decade of the Brain” as it opened doors to a number of emerging interventions for altering brain functions. We generally focus on the positive potential associated with the discovery, but, of course, what it really indicated was that the brain is continually being sculpted by its experiences, both external and internal. Neuroplasticity can shape the patterns of brain functioning through habit and happenstance, or it can be directed through particular experiences to function better in a more deliberately determined manner. Applying what we have learned in the area of improved emotion regulation will continue to be one of the most important uses of the knowledge and skills we have acquired. Good emotion regulation is directly related to improved brain regulation. Neurofeedback has proven to be a highly beneficial approach for improving brain regulation and continues to contribute to improvements in emotion regulation skills.