Phenotype evaluation of the EEG was proposed in a paper in 2005 published in Clinical Electroencephalography and Neurophysiology. The retrospective analysis of many decades of experience has since been actively evaluated, from published works focusing on basic neuroscience (J. Pop-Jordanov), and the work from Holland on medication response prediction (M. Arns).
Additionally there was publication of a prospective study applying phenotype-driven Neurofeedback protocols in clinical addiction, looking at the neuro-cognitive impacts of the approach, as well as the impacts on addiction behavior itself.
The medication prediction work and basic neuroscience studies led to a newer integration of the phenotype model, the ‘brain-rate’ work by Professor Dr Jordan Pop-Jordanov and the European Vigilance model (Bente, 1964) popularised by the work of Professor Dr Gerald Ulrich of Germany.
These validation studies will be reviewed and I will attempt to briefly present a more integrated model, which is ‘in press’ at a societal newsletter level publication, and will be submitted with a more formal systematic evaluation of the vigilance and phenotype models in an ADHD population (this later done was done with M. Arns, and W. Van den Bergh).