The resident endogenous SCs existing in patients could also be a potential target for ED therapy. The aim of this review was to summarize contemporary evidence regarding:
(1) SC niche and SC biological features in vitro;
(2) localization and mobilization of endogenous SCs;
(3) existing evidence of penile endogenous SCs and their possible mode of mobilization.
We performed a search on PubMed for articles related to these aspects in a wide range of basic studies. Together, numerous evidences hold the promise that endogenous SCs would be a novel therapeutic approach for the therapy of ED.