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Predictors of phosphodiesterase type-5 inhibitor (PDE-5I) use in an Australian cohort of men who have sex with men (MSM)

Predictors of phosphodiesterase type-5 inhibitor (PDE-5I) use in an Australian cohort of men who have sex with men (MSM)

Phosphodiesterase type-5 inhibitors (PDE-5Is) have been successful in assisting men with erectile dysfunction (ED). Research has suggested that these medications are used recreationally in both heterosexual males and men who have sex with men (MSM). The current study was undertaken to assess the impact of ED and other factors on PDE-5I use in an Australian MSM population.

A cross-sectional internet based survey of Australian MSM was undertaken. Participants were asked to provide information on their use of PDE-5Is, demographic variables and to complete the MSM version International Index of Erectile Function (IIEF-MSM). The six item ED score (EF-6) was used in the analysis. Univariate and binary logistic regression (BLR) analyses were undertaken for those attempting active anal intercourse (GP 1, n=324) and those attempting all forms of sexual activity (GP 2, n=237). Independent variables included in the BLR were age, casual partner, regular partner, smoking and EF-6 score.

Univariate analysis of GP 1 and 2 found age, EF-6 and having sex with casual partners were associated with PDE-5I use. BLR analysis found significant models for both analyses [GP1: (N = 308, χ2 = 95.8, df = 2, p <0.0005; GP2: N= 227, χ2 = 73.44, df = 2, p < 0.0005]. Age [GP1: OR 1.07 (95%CI 1.05, 1.10); GP2: OR 1.07 (95% CI 1.06, 1.09)] and EF-6 [GP1: OR 0.90 (95% CI 0.86, 0.94); GP2: OR 0.89 (95% CI 0.85, 0.93)] were found to be predictors of PDE-5I use for both analyses.

The current results suggest that ED and age are the primary factors predicting PDE-5I use in this sample. While sex with a casual partner was associated with PDE-5I use in the uivariate analyses, which may suggest a contribution of recreational use or psycho-social factors, it did not remain significant in the multivariate analyses.

Speakers: Brendan Crozier
Conference: ASHM 2013
Areas of Interest / Categories: Erectile Dysfunction, Homosexuality


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