Abnormal profiles of polyunsaturated fatty acids in the plasma phospholipids were observed in patients with closed head injuries, indicating that the metabolic response to injury encompasses changes in the metabolism of polyunsaturated fatty acids which are rapid in onset and qualitatively similar to those seen in essential fatty acid deficiency (Alden, Svingen et al. 1987). …. Learning and attention deficits and other neurodegenerative damage following TBI are ameliorated by supplementation with the Omega 3 fatty acid DHA from fish oils Supplementation with fish oils and co-factors has been found to be an effective treatment to ameliorate attention. Consequently it makes sense to treat patients with TBI as if there are Omega 3 EFA deficiencies.