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Overview of the most prevalent metabolic syndrome component causing more sexual dysfunction in postmenopausal women

Overview of the most prevalent metabolic syndrome component causing more sexual dysfunction in postmenopausal women

Several studies have demonstrated the great impact of the climacteric on sexual function, which can lead to dysfunctions and important changes in women’s health. The interest in studying the sexual function of female patients diagnosed with Metabolic Syndrome (MetS) has been recent, and researchers point out to the fact that there exist few studies focusing on the female sexuality. 

Objective: To create an overview of the most prevalent MetS components causing increased sexual dysfunction (SD) in postmenopausal women.

Methods: This is a case-control study. The group consisted of postmenopausal women seeking treatment at the Santa Casa de São Paulo Medical School, in the period between February 2011 and February 2013. The women considered as being postmenopausal were those with amenorrhea ≥1 year and FSH ≥ 30 mUI/mL. The MetS diagnosis was determined based on the guidelines defined by the ATP III: Abdominal circumference ≥88 cm; HDL-cholesterol ≤50 mg/dL; triglycerides ≥150 mg/dL; arterial blood pressure ≥130/85 mmHg; and fasting glucose ≥110 mg/dL. The women considered to present with MetS were those with at least three of the components described. The assessment of their sexual function was performed using the Female Sexual Function Index (FSFI). Postmenopausal women with an active sexual life were included in the study and submitted to standardized anamnesis.

Results: All of the MetS diagnosis components, including systemic arterial hypertension (SAH), when analysed separately using the Chisquare test, were associated with higher levels of SD, with significant differences between the Study and Control Groups (p < 0.001).

Conclusion: When we analyse the diagnostic parameters for MetS, we find significant differences when we compare them with those from the control group in all these aspects. We observed that some factors have already been singly described in the literature as risk factors. In our study, however, all of them had an important role, which led us to understand that MetS is the main predictor of SD when it is compared to any isolated component of the syndrome.

Areas of Interest / Categories: Sexual Dysfunction