Please Sign In or Create an account
Early onset GID and its effects on hippocampus measured by neuropsychological tests and MRI

Early onset GID and its effects on hippocampus measured by neuropsychological tests and MRI

Therefore, we explored GID children/adolescence under the age of 18 with regard to their neuropsychological (cognitive testing) and morphological brain function (MRI) before starting GnRHR blockage treatment.
Astonishingly we found highly significant differences between GID and controls in cognitive function showing reduced verbalization and executive function abilities by at the same time significantly atrophic hippocampus and cerebellum tissue in GID patients. Whether these effects will be reversible by treatment, or whether they could be correlated to psychological functioning in those kids has to be shown by our group over time.
Nevertheless in summary, before starting long-term treatment with a GnRH agonist, effects on cognitive function and brain morphology should be carefully explored before long term exposure and because of the recent increasing literature on those functions in other study populations.

Speakers: Ira Haraldsen
Conference: WAS Glasgow 2011