Methods: Guy2Guy is a five-week, text messaging-based HIV prevention program developed and tested in a randomized controlled trial of 302, 14–18 year-old GBQ men enrolled online nationally. The sample was purposefully recruited to ensure diversity: in race (40% non-White), ethnicity (23% Hispanic), rural (22%) settings, age (40% 14–15 year olds), and sexual experience (50% never had anal or vaginal sex). The control group received basic HIV prevention messages as well as “healthy lifestyle” messages (e.g., self-esteem). Intervention-end outcome measures were: 1) the number of condomless sex acts (CSA; anal or vaginal) and 2) HIV testing over the 5-week study period. Negative binomial regression quantified the difference in CSA rates and logistic regression quantified differences in HIV testing between the study groups.
Results: Among the 96% of participants who provided intervention end data, the number of CSAs during the study ranged from 0–92. The median number of CSAs were similar for intervention and control participants (p = 0.87). Once baseline number of CSAs were taken into account, the intervention end rate was 61% lower for intervention versus control youth (aIRR = 0.39, 95% CI: 0.16, 0.96). Eighteen percent of participants reported getting tested during the five-week study period. Compared to 13% of control participants, 24% of intervention participants reported being tested since baseline (Pearson X2(1) = 6.1, p = 0.01). Even after adjusting for HIV testing history, the odds of HIV testing during the study period were two-fold higher for intervention versus control participants (aOR = 2.37, 95% CI: 1.23, 4.56).
Conclusion: Exposure to Guy2Guy appears to be related to increased HIV preventive behaviors at intervention-end.
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