Access to age appropriate, gender-sensitive sexuality education in a socio-culturally diverse country is very challenging especially where the culture of silence on sexuality issues is the norm. Thus when Action Health Incorporated (AHI) a youth serving non-governmental organization in Nigeria led advocacy for access to sexuality education in Nigeria, the catalytic document for this initiative was the development, endorsement of, and public release of the National Guidelines for Sexuality Education in Nigeria. This publication was adapted from the Guidelines for Sexuality Education produced by the Sexuality Information and Education Council of the United States (SIECUS).