Differentiation of family members is the capacity to function as an autonomous self while remaining connected to significant others. It involves an internal process of regulating emotions and activating thinking as well as an interpersonal process of managing relationship pulls to fuse with others or to distance. Theories posit that families pass on levels of differentiation across generations. There are also variations within a generational family according to the amount of emotional intensity each child/member is caught up in. Exploring the interplay of family differentiation with levels of anxiety and acute events will be central to Jenny’s presentation. A case example is used to illustrate and discuss the clinical implications and treatment approaches.